2009年,华东理工大学生物工程专业,学士学位;
2012年,华东理工大学微生物与生化药学专业,硕士学位;
2018年,慕尼黑工业大学生物信息学专业,博士学位;
2018年,华侨大学医学院,讲师;
2023年,伟德BETVlCTOR1946,助理教授
B.S. 2009, East China University of Science and Technology, Bioengineering;
M.S. 2012, East China University of Science and Technology, Microbiological and Biochemical Pharmacy;
Ph.D. 2018, Technical University of Munich, Bioinformatics;
Lecture, School of Medicine, Huaqiao University, 2018-2023
Assistant Professor, School of Life Sciences, Xiamen University, 2023 to present
研究工作聚焦于 RNA 相关领域,主要涉及新型 RNA 结构元件(如核酶)的鉴定及其结构、进化和功能研究,RNA 参与的翻译过程的调控机制研究,以及基于转录组学的疾病诊断和治疗研究等。
My research focuses on the field of RNA, primarily involving the identification, structure determination, evolution, and functional studies of novel RNA structural elements, such as ribozymes. Additionally, I investigate the regulatory mechanisms of the translation process involving RNA, and conduct research in disease diagnosis and treatment based on transcriptomics. My work contributes to understanding the roles of RNA in cellular processes and its implications for potential therapeutic applications.
代表性论文(# co-first author, * Corresponding author):
1. Chen, Y.#, Qi, F.#*, Gao, F., Cao, H., Xu, D., Salehi-Ashtiani, K., Kapranov, P.* Hovlinc is a recently evolved class of ribozyme found in human lncRNA. Nat Chem Biol. 2021,17(5):601–607.
2. Qi, F., Frishman, D. Melting temperature highlights functionally important RNA structure and sequence elements in yeast mRNA coding regions. Nucleic Acids Res. 2017,45(10):6109–6118.
3. Krafczyk, R.#, Qi, F.#, Sieber, A., Mehler, J., Jung, K., Frishman, D.*, Lassak, J.* Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria. Commun Biol. 2021,4(1):589.
4. Qi, F., Motz, M., Jung, K., Lassak, J., Frishman, D. Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation. PLOS Comput Biol. 2018,14(2):e1005987.
5. Qi, F., Gao, F., Cai, Y., Han, X., Ni, J., Sun, J., Huang, S., Chen, S., Wu, C., Kapranov, P. Complex age- and cancer-related changes in human blood transcriptome – implications for pan-cancer diagnostics. Front Genet. 2021,12:746879.
6. Qi, F., Cai, Y., Chen, J., Han, X., Xia, Q., Kapranov, P. Traditional Chinese medicine treatment, Gua Sha, can induce subtle molecular changes in gene expression. Biomed Environ Sci. 2023, 36(5): 441-451.
荣誉、奖励及参加学术团体的情况:
福建省高层次人才(C类)
厦门市高层次人才(C类)
厦门市高层次留学人才
厦门市骨干人才