2004年,伟德国际官网登录入口生物科学专业,学士学位;
2009年,伟德国际官网登录入口生物化学与分子生物学专业,博士学位;
2009-2010年,美国犹他大学病理系,博士后;
2011年,伟德BETVlCTOR1946,助理教授
2022年,伟德国际官网登录入口科学学院,副教授
B.S. School of Life Sciences, Xiamen University, 2004;
Ph.D. School of Life Sciences, Xiamen University, 2009;
Postdoctoral Fellow, School of Medicine, University of Utah, 2009-2010;
Assistant Professor, School of Life Sciences, Xiamen University, 2011-2022;
Associate Professor, School of Life Sciences, Xiamen University, 2022-present.
以重大危害遗传病诊断和肿瘤基因突变检测为模型,从事分子诊断新技术和新方法的开发。 My research focuses on developing new techniques and methods for molecular diagnosis, with goals to provide better ways to diagnose human genetic disorders and detect somatic gene mutations in cancer.
代表性论文(# co-first author, * Corresponding author):
1. Huang Q, Chen D, Du C, Liu Q, Lin S, Liang L, Xu Y, Liao Y, Li Q. Highly multiplex PCR assyas by coupling the 5'-flap endonuclease activity of Taq DNA polymerase and molecular beacon reporters. PNAS, 2022, 119(9):e2110672119.
2. Huang Q, Wang X, Tang N, Yan T, Chen P*, Li Q*. Simultaneous Genotyping of α-Thalassemia Deletional and Nondeletional Mutations by Real-Time PCR-Based Multicolor Melting Curve Analysis. J Mol Diagn, 2017, 19(4):567-574.
3. Wang X, Hong Y, Cai P, Tang N, Chen Y, Yan T, Liu Y, Huang Q*, Li Q*. Rapid and Reliable Detection of Nonsyndromic Hearing Loss Mutations by Multicolor Melting Curve Analysis. Sci Rep, 2017, 7:42894.
4. Xia Z, Chen P, Tang N, Yan T, Zhou Y, Xiao Q, Huang Q*, Li Q*. Rapid detection of G6PD mutations by multicolor melting curve analysis. Mol Genet Metab, 2016, 119(1-2):168-73.
5. Huang Q, Wang X, Tang N, Zhu C, Yan T, Chen P*, Li Q*. Rapid detection of non-deletional mutations causing α-thalassemia by multicolor melting curve analysis. Clin Chem Lab Med, 2016, 54(3):397-402.
6. Liao Y, Wang X, Sha C, Xia Z, Huang Q*, Li Q*. Combination of fluorescence color and melting temperature as a two-dimensional label for homogeneous multiplex PCR detection. Nucleic Acid Research, 2013, 41(7):e76.
7. Xiong F#, Huang Q#, Chen X, Zhou Y, Zhang X, Cai R, Chen Y, Xie J, Feng S, Wei X, Xiao Q, Zhang T, Luo S, Yang X, Hao Y, Qu Y, Li Q , Xu X. A Melting Curve Analysis–Based PCR Assay for One-Step Genotyping of β-Thalassemia Mutations: A Multicenter Validation. J Mol Diagn, 2011,13(4): 427-435.
8. Huang Q, Liu Z, Liao Y, Chen X, Zhang Y, Li Q . Multicolor Fluorescence Melting Curve Analysis for Detection of Multiple Mutations with Self-Quenched Probes. PLoS ONE, 2011, 6(4):e19206.
9. Huang Q, Hu Q, Li Q. Identification of 8 Foodborne Pathogens by Multicolor Combinational Probe Coding Technology in a Single Real-Time PCR. Clinical Chemistry, 2007, 53(10): 1741-1748.
荣誉、奖励及参加学术团体的情况:
1. “均相多靶核酸检测关键技术研究与应用”获2020年度福建省技术发明奖二等奖, 排名第二, 2022.
2. 专利“一种核酸序列变异的检测方法”获2019年福建省专利奖一等奖, 排名第二, 2020。
3. 专利“一种核酸序列变异的检测方法”获2017年第六届厦门市专利奖特等奖,排名第二, 2017.
4. 获评伟德国际官网登录入口2021年度德贞社会课堂基金优秀指导教师,2022
5. 指导项目“禾芯科技—打造中国转基因检测的核心力量”获得全国大学生生命科学竞赛(创新创业类)一等奖, 2021
6. 获伟德国际官网登录入口2021年度“中国工商银行奖教金”, 2021.
7. 获伟德国际官网登录入口第十五届青年教师技能比赛二等奖及最佳课件奖, 2020