2006年，东北师范大学生物学专业，学士学位；
2012年，伟德国际官网登录入口生物化学与分子生物学专业，博士学位；
2012-2015年，伟德国际官网登录入口附属中山医院，博士后；
2015-2023年，伟德BETVlCTOR1946，助理教授；
2023年至今，伟德BETVlCTOR1946，副教授；
2020年至今，伟德BETVlCTOR1946，特任副研究员。
B.S. 2006, Northeast Normal University, Biology;
Ph.D. 2012, Xiamen University, Biochemistry and Molecular Biology;
Postdoctoral Fellow, Zhongshan Hospital, Xiamen University, 2012-2015;
Assistant Professor, School of Life Sciences, Xiamen University, 2015 to Present.

细胞代谢及其信号调控

代表性论文(^# co-first author, ^* Corresponding author):

1. Wang J, Zheng LF, Ren S, Li DL, Chen C, Sun HH, Liu LY, Guo H^*, Zhao TJ^*. ARF6 plays a general role in targeting palmitoylated proteins from golgi to the plasma membrane. J Cell Sci. 2023 Jul 18:jcs.261319. doi: 10.1242/jcs.261319. Online ahead of print.
2. Guo H^#, Wang J^#, Ren S^#, Zheng LF^#, Zhuang YX, Li DL, Sun HH, Liu LY, Xie C, Wu YY, Wang HR, Deng X, Li P, Zhao TJ^*. Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nat Commun. 13(1):6004, 2022.
3. Shen H^#, He T^#, Wang S^#, Hou LF^#, Wei YX, Liu YJ, Mo CL, Zhao ZH, You WX, Guo HL^*, Li BA^*. SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex. Theranostics, 12(18): 7699-7716, 2022.
4. Hao JW^#, Wang J^#, Guo H^#, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, Wang X, Xie C, Hong L, Huang X, Wang HR, Li CB, Liang B, Chen S, Zhao TJ^*. Nat Commun. 11(1):4765, 2020.
5. Wang J^#, Hao JW^#, Wang X^#, Guo H^#, Sun HH, Lai XY, Liu LY, Zhu M, Wang HY, Li YF, Yu LY, Xie C, Wang HR, Mo W, Zhou HM, Chen S, Liang G, Zhao TJ^*. DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep. 26(1):209-221, 2019.
6. Zhang YL^#, Guo HL^#, Zhang CS^#, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, Lian G, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC^*. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation. Cell Metab.18(4):546-555, 2013.
7. Guo HL^#, Zhang C^#, Liu Q^#, Li Q, Lian G, Wu D, Li X, Zhang W, Shen Y, Ye Z, Lin SY, Lin SC. The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation. Cell Res. 22: 1246-1257,2012.

荣誉、奖励及参加学术团体的情况: