Title: Understanding Health and Longevity：Insights from Metabolic Signals

Speaker: Dr. Meng Wang

Time: November 7, 2024 at 10:15 AM

Venue: Academic Report Hall, Yuejin Building

Introduction of the reporter:Dr. Meng Wang is currently a Senior Group Leader at HHMI Janelia Research Campus. Dr. Wang joined the faculty of Baylor College of Medicine in 2010. Before moving to Janelia in 2022, she was an HHMI Investigator, a Professor and the Robert C. Fyfe Endowed Chair on Aging at Baylor College of Medicine (BCM), as well as a co-director of the BCM Genetics and Genomics Graduate Program. Dr. Wang’s research focuses on the molecular mechanisms governing somatic aging, reproductive senescence, and lipid metabolism, and their sophisticated interrelationship, through harnessing the power of functional genomics, metabolomics, chemical engineering and optical biophysics. Her group uncovered the first lysosome-to-nucleus retrograde lipid messenger pathway, provided new regulatory mechanisms of reproductive longevity, and demonstrated a novel mode of signaling communication between bacteria and mitochondria in regulating host’s lipid metabolism and longevity. Technological developments in Dr. Wang’s laboratory have provided brand new ways to visualize and track lipid molecules as a function of time and space in living cells and organisms. She is the recipient of NIH Director’s Pioneer Award, Peter O’Donnell Award, HHMI Faculty Scholar Award, ASCB Gibco Emerging Leader Prize, ASCB Early Career Life Scientist Award, and Glenn Award for Research in Biological Mechanisms of Aging. She is an elected fellow of the American Association for the Advancement of Science and the American Society for Cell Biology.