Education

1991-1996, B.Sc., Tsinghua University, Bioscience & Biotechnology;

1997-2000, M.Sc., National University of Singapore, Microbiology;

2000-2004, PhD., National University of Singapore, Computational Science.

Professional Experience

2003-2008, Associate Professor, Xiamen University;

2008-present, Professor, Xiamen University.

Research Area

The Ji’s BADD group focuses the long-term research interests on three areas: (1) Systems Computational Drug Toxicity: utilize systems biology methodology and AI technology to assist in mechanistic exploration & large-scale prediction of clinical drug toxicity. (2) Biomedical Big Data: exploit multimodal data to unveil the genetic basis of complex diseases and whereby discover new therapeutic targets. (3) Systems Biology: develop new methods to integrate multi-omics data for systematic investigation of sperm maturation mechanism and functional understanding of non-coding RNAs.

Selected Publications

1.Zhou J^#, Wu L^#, Xu P, Li Y, Ji ZL^*, Kang X^*. Filamin A Is a Potential Driver of Breast Cancer Metastasis via Regulation of MMP-1. Frontiers in Oncology. 2022 Mar 11; 12:836126.
2.Chen X^#, Li Y^#, Huang Q, Lin X, Wang X, Wang Y, Liu Y, He Q, Liu Y, Wang T^*, Ji ZL^*, Li Q^*. Segmental duplication as potential biomarkers for non-invasive prenatal testing of aneuploidies. EBioMedicine. 2021 Aug; 70:103535.
3.Liu K, Ding RF, Xu H, Qin YM, He QS, Du F, Zhang Y, Yao LX, You P, Xiang YP, Ji ZL^*. Broad-Spectrum Profiling of Drug Safety via Learning Complex Network. Clinical Pharmacology & Therapeutics. 2020 Jun; 107(6):1373-1382.
4.Tang J, Tang XX, Qin YM, He QS, Yi Y, Ji ZL^*. Karst rocky desertification progress: Soil calcium as a possible driving force. Science of the Total Environment. 2019; 649: 1250-1259.
5.Huang LH, He QS, Liu K, Cheng J, Zhong MD, Chen LS, Yao LX, Ji ZL^*. ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Research. 2018 Jan; 46: D911-17.