 | Qingyan Xu, Ph.D. Associate Professor. Tel: +86-592-2180328 E-mail: xuqingyan@yahoo.com |
Education
1992, B. Sc., West China University of Medical Science;
1995, M. Sc., West China University of Medical Science;
2004, Ph. D., Xiamen University.
Professional Experience
2006-2007, Postdoctoral Fellow, Louis-Pasteur University, Strasbourg, France;
Lecturer/Assistant Professor/Associate Professor, School of Life Science, Xiamen University, 1995 to Present.
Research Area
Microbial Pharmacology. The main research area lies in Microbial Pharmacology. More than antibacterial and antitumor activities, we focus on the research of compounds with anti-TNF-α activity. We hope to find inhibitors that block the necrosis signaling pathway of TNF-α from microorganisms.
Selected Publications
1. Liu J L., Hu Z Y., Huang Y J., Zheng Z H, Xu Q Y*. Aspochalasin U, a moderate TNF-α inhibitor from Aspergillus sp[J]. Journal of Antibiotics. 2012, 65 : 49-52.
2. Liu J L, Hu Z Y, Xu Q Y*. 3 '-(3-Hydroxyphenyl)-4-methylspiro benzo e 1,4 diazepine-3,2 '-oxirane -2,5(1H, 4H)-dione[J]. Acta Crystallographica Section E - Structure Reports Online, 2011, 67: O1670 - U1532.
3. Zimmermann M, Atmanene C, Xu Q Y, Fouillen L, Van Dorsselaer A, Bonnet D, Marsol C, Hibert M, Sanglier-Cianferani S, Pigault C, McNamara LK, Watterson DM, Haiech J*, Kilhoffer MC. Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter[J]. PLoS ONE, 2010, 5(11). E14120.
4. Zhan Y Y, Du X P, Chen H Z, Liu J J, Zhao B X, Huang D H, Li G D, Xu Q Y, Zhang M Q, Weimer B C, Chen D, Cheng Z, Zhang L R, Li Q X, Li S W, Zheng Z H, Song S Y, Huang Y J, Ye Z Y, Su W J, Lin S C, Shen Y M, Wu Q*. Cytosporone B is an agonist for nuclear orphan receptor Nur77 [J]. Nature Chemical Biology, 2008, 4(9):548-556.
5. Xu Z, Xu Q Y, Zheng Z H, Huang Y J*. Kribbella amoyensis sp. nov., isolated from the rhizosphere soil of a pharmaceutical plant, Typhonium giganteum Engl [J]. International Journal of Systematic and Evolutionary Microbiology, 2011. PMID: 21705443.
