Education

1991, B.Sc., Shanghai Fisheries University;

1996-2001, Ph.D., Nagasaki University, Japan.

Professional Experience

1991-1996, Research Assistant, Fisheries Research Institute of Fujian;

2002-2004, Postdoctoral Fellow at School of Life Science, Xiamen University;

2004-present, Associate Professor, School of Life Science, Xiamen University.

Research Area

Our research focuses on: 1) Screening of inhibitors of tyrosinase (the key enzyme of melanin formation), the mechanism of inhibiting the enzyme, the regulation mechanism of melanin formation and its application in whitening cosmetics and fruit and vegetable preservation; 2) Effects of prenatal tea polyphenols (EGCG) supplementation on health of adult mice.

Selected Publications

1.Wu W, Wu MY, Dai T, Ke LN, Shi Y, Hu J^*, Wang Q^*. Terphenyllin induces CASP3-dependent apoptosis and pyroptosis in A375 cells through upregulation of p53. Cell Communication and Signaling. 2024; 22: 409.
2.Hu JJ^#, Chen B^#, Qu SJ, Liu SJ, Yang XY, Qiao K, Su YC, Liu ZH, Chen XE^*, Liu ZY^*, Wang Q^*. Anti-Melanogenic Effects of Takifugu flavidus Muscle Hydrolysate in B16F10 Melanoma Cells and Zebrafish. Marine Drugs. 2024; 22, 206.
3.Ou KL^#, Zhang Q^#, Xi FF, Ni HZ, Lu JB, Lyu XJ, Wang CG, Li QY^*, Wang Q^*. Prenatal EGCG consumption impacts hepatic glycogen synthesis and lipid metabolism in adult mice. International Journal of Biological Macromolecules. 2024; 260: 129491.
4.Xia SY, Xi FF, Ou KL, Zhang Y, Ni HZ, Wang CG, Wang Q∗. The effects of EGCG supplementation on pancreatic islet α and β cells distribution in adult male mice. Journal of Nutritional Biochemistry. 2024; 124: 109529.
5.Wu YL, Liu GS, Li ZP^*, Chen ML^*, Wang Q^*. ATG13 is involved in immune response of pathogen invasion in blood clam Tegillarca granosa. Frontiers in Veterinary Science. 2023; 10: 1141284.
6.Ou KL^#, Zhang SL^#, Song JL, Fang L, Xia SY, Huang J, Wang Q^*, Wang CG^*. Prenatal EGCG consumption causes obesity and perturbs glucose homeostasis in adult mice. Journal of Nutritional Biochemistry. 2022; 111, 109179.
7.Xia SY^#, Ou KL^#, Zhang SL, Huang J, Fang L, Wang CG, Wang Q^*. EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms. Food and Chemical Toxicology. 2022; 167, 11330.
8.Chen B^#, Yu L^#, Wu JN, Qiao K, Cui LL, Qu HD, Su YC, Cai SL, Liu ZY^*, Wang Q^*. Effects of Collagen Hydrolysate from Large Hybrid Sturgeon on Mitigating Ultraviolet B-Induced Photodamage. Frontiers in Bioengineering and Biotechnology. 2022; 10: 908033.
9.Liu TT, Liu XT, Huang GL, Liu L, Chen QX, Wang Q^*. Theophylline Extracted from Fu Brick Tea Affects the Metabolism of Preadipocytes and Body Fat in Mice as a Pancreatic Lipase Inhibitor. International Journal of Molecular Sciences. 2022; 23(5): 2525.
10.Chen B^#, Chen HH^#, Qu HD, Qiao K, Xu M, Wu JN, Su YC, Shi Y, Liu ZY^*, Wang Q^*. Photoprotective effects of Sargassum thunbergii on ultraviolet B-induced mouse L929 fibroblasts and zebrafish. BMC Complementary Medicine and Therapies. 2022, 22:144.
11.Feng HM, Qiao K, Wang CC, Chen B, Xu M, Hao H, Huang Z, Liu ZY^*, Wang Q^*. Multi-Omics Analysis of Gene and Protein Candidates Possibly Related to Tetrodotoxin Accumulation in the Skin of Takifugu flavidus. Marine Drugs. 2021; 19: 639-658.
12.Zhang SL^#, Ou KL^#, Huang J, Fang L, Wang CG, Wang Q^*. Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms. Food and Chemical Toxicology. 2021; 157: 112588.
13.Hu YH, Zhou Y, Hu XH, Chen QL, Shi Y, Zhuang JX^*, Wang Q^*. Cefotaxime sodium inhibited melanogenesis in B16F10 cells by cAMP/PKA/CREB pathways. Process Biochemistry. 2021; 110: 63-70.
14.Liu XT^#, Liu TT^#, Xu HL, Chen QX^*, Wang Q^*. Inhibitory kinetics and bioactivities of Nuciferine and Methyl Ganoderate on Mucor miehei lipase and 3T3-L1 preadipocytes. International Journal of Biological Macromolecules. 2020; 163: 1719-1728.
15.Chen YM, Li C, Zhang WJ, Shi Y, Wen ZJ, Chen QX, Wang Qin^*. Kinetic and computational molecular docking simulation study of novel kojic acid derivatives as anti-tyrosinase and antioxidant agents. Journal of Enzyme Inhibition and Medicinal Chemistry. 2019; 34(1): 990-998.
16.Chen YM^#, Su WC^#, Li C, Shi Y, Chen QX, Zheng J, Tang DL, Chen SM, Wang Q^*. Anti-melanogenesis of novel kojic acid derivatives in B16F10 cells and zebrafish. International Journal of Biological Macromolecules. 2019; 123: 723-731.
17.Yu H, Fu QR, Huang ZJ, Lin JY, Chen QX, Wang Q^*, Shen DY^*. Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway. Oncology Reports. 2019, 41: 213-223.