TONG Mengsha, Ph.D.
Assistant Professor
Bioinformatics
E-mail：mstong@xmu.edu.cn
Education and Work experience
B.Sc. Pharmacy, Fujian Medical University, 2013
M.Sc. Bioinformatics, Fujian Medical University, 2016
Ph.D. Bioinformatics, Tsinghua University, 2019
Research Area
Using bioinformatics technology to identify cancer prognostic markers and drug targets based on single cell-omics data
Selected Publications(* Corresponding author)：
1. Tong M#,Yu C#, Shi J#, Huang W#, Ge S#, Liu M, Song L, Zhan D, Xia X, Liu W, Feng J, Shi W, Ji J, Gao J, Shi T, Zhu W, Ding C, Wang Y, He F*, Shen L*, Li T*, Qin J*.Phosphoproteomics Enables Molecular Subtyping and Nomination of Kinase Candidates for Individual Patients of Diffuse-Type Gastric Cancer. iScience. 2019 Nov 6;22:44-57. doi: 10.1016/j.isci.2019.11.003.
2. Tong M#, Yu C#, Zhan D, Zhang M, Zhen B, Zhu W, Wang Y, Wu C, He F*, Qin J*, Li T* Molecular subtyping of cancer and nomination of kinase candidates for inhibition with phosphoproteomics: reanalysis of CPTAC ovarian cancer. EBioMedicine. 2019 Feb;40:305-317. doi: 10.1016/j.ebiom.2018.12.039
3. Tong M#, Zheng W#, Li H, Li X, Ao L, Shen Y, Liang Q, Li J, Hong G, Yan H, Cai H, Li M, Guan Q, Guo Z.*. Multi-omics landscapes of colorectal cancer subtypes discriminated by an individualized prognostic signature for 5-fluorouracil- based chemotherapy. Oncogenesis. 2016 Jul 18;5(7):e242. doi: 10.1038/onc sis.2016.51.
4. Tong M, Zheng W, Lu X, Ao L, Li X, Guan Q, Cai H, Li M, Yan H, Guo Y, Chi P, Guo Z* Identifying clinically relevant drug resistance genes in drug-induced resistant cancer cell lines and post-chemotherapy tissues. Oncotarget 2015 Dec 1;6(38):41216-27. doi: 10.18632/ oncotarget.5649.
5. Shen Y#, Tong M#, Liang Q, Guo Y, Sun HQ, Zheng W, Ao L, Guo Z*, She F*. Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells. The pharmacogenomics journal 2018 Jan;18 (1):23-28. doi: 10.1038/tpj.2016.91.
