Huiling GUO, Ph.D.

Assistant Professor

Tel: 13950085767

E-mail: ghuiling@xmu.edu.cn

Education

2006, B.S., Northeast Normal University

2012, Ph.D., Xiamen University

Research Area

2012-2015, Postdoctoral Fellow at Zhongshan Hospital, Xiamen University;

2015/03-present, Assistant Professor, School of Life Sciences, Xiamen University

Research Area

Cell metabolism and signal regulation

Selected Publications

1. Zhang CS, Liu Q, Li M, Lin SY, Peng Y, Wu D, Li TY, Fu Q, Jia W, Wang X, Ma T, Zong Y, Cui J, Pu C, Lian G, Guo H, Ye Z, Lin SC*. RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect. Cell Res., 2015, 25(9):1025-1042.

2. Zhang CS, Jiang B, Li M, Zhu M, Peng Y, Zhang YL, Wu YQ, Li TY, LiangY, Lu Z, Lian G, Liu Q, Guo H, Yin Z, Ye Z, Han J, Wu JW, Yin H, Lin SY,Lin SC*. The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism. Cell Metab. 2014 20(3):526-540

3. Zhang YL, Guo HL, Zhang CS, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, LianG, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC*. AMP as alow-energy charge signal autonomously initiates assembly of

AXIN-AMPK-LKB1 complex for AMPK activation. Cell Metab.18(4):546-555, 2013. (Co-first author)

4. Guo HL, Zhang C, Liu Q, Li Q, Lian G, Wu D, Li X, Zhang W, Shen Y, Ye Z,Lin SY, Lin SC. TheAxin/TNKS complex interacts with KIF3A and isrequired for insulin-stimulated GLUT4 translocation. Cell Res.22: 1246-1257,2012.

5. Li Q, Lin SY., Wang X, Lian, G, Lu Z, Guo H, Ruan K, Wang Y, Ye Z, Han J,Lin SC*. Axin determines cell fate by controlling the p53 activationthreshold after DNA damage. Nat. Cell. Biol. 11, 1128-1135, 2009.